Two people were shot to death in an office building in Jerusalem's Jaffa street, one of the busiest streets in the city center.
The shooter, a security guard, entered an office on the third floor of the Clal Center near Jerusalem's Mahane Yehuda market, and shot the owner and a female employee.
He then tried to flee the scene but a policeman and an ex-cop who heard the shots chased after him and stopped him.
The circumstances behind the event are unclear.
The shooter has been taken into custody.
"A man in his forties entered one of the offices and shot a man in his fifties and a woman in her twenties," said Brigadier-General Amnon Alkalai.
Jerusalem Mayor Nir Barkat arrived as the scene and said, "this is a tragedy. It's a very sad case. Our hearts are with the victims' families."